Perindopril is an inhibitor of ACE (angiotensin converting enzyme), it is of hypotensive, vasodilating, cardioprotective, natriuretic action. It reduces
hypertrophy of aortic ventricle and prevents proliferation of smooth muscle cells of vessels, induces inverse development of hypertrophy of vascular wall, restores flexibility of large vessels and endothelium function, in particular the ability to release NO. It is of retard hypotensive action lasting during repeated intake. In chronic cardiac insufficiency it reduced clinical symptoms and increases tolerance of physical load.